Doctor facing a large fiery heart symbolizing urgent ATTR-CM awarenessDoctor facing a large fiery heart symbolizing urgent ATTR-CM awareness

ATTR-CM IS AN UNDERDIAGNOSED, RAPIDLY PROGRESSIVE, DEBILITATING AND FATAL DISEASE1
 

LEARN ABOUT THE DIFFERENT CAUSES OF HF IN ATTR-CM, AND HOW THE DISEASE PROGRESSES 

PATIENTS WITH ATTR-CM ARE ALREADY IN YOUR PRACTICE2–4

Up to

~1 IN 6

patients with LVH2,3

and

~1 IN 7

patients with 
HFpEF2,4

are likely to have ATTR-CM

 If your patient is experiencing heart failure symptoms, think ATTR-CM 

ANY DELAY IN DIAGNOSIS OF ATTR-CM CAN RESULT IN PROGRESSIVE DISABILITY AND WORSE OUTCOMES5–7

ATTR-CM is an underdiagnosed, rapidly progressive, debilitating 
and fatal disease.1 Life expectancy for patients with ATTR-CM is 
2–6 years from the point of diagnosis1

Learn about how the build-up of toxic misfolded TTR* deposits causes ATTR-CM, and the impact of disease progression

*Toxic TTR refers to the misfolded TTR proteins in patients with ATTR-CM which aggregate into amyloid fibrils, causing multisystemic deposits.8,9

Medical illustration of a heart showing infiltrated myocardium
Infographic showing LVH and HFpEF indicators in patients over 60 years old

KNOW THE RED FLAG SYMPTOMS THAT SHOULD RAISE SUSPICION OF ATTR-CM

Patients with ATTR-CM are already in your clinic – look out for key clinical signs and investigative findings to uncover the disease2–4

Learn about the clinical signs and symptoms of ATTR-CM that should prompt confirmatory assessments

TIMELY DIAGNOSIS IS CRITICAL6,10

Diagnose ATTR-CM in two key steps and act fast when ATTR-CM 
has been confirmed: rapidly initiate specific ATTR-CM treatment, 
or refer to a centre that can1,6,7,11

Learn about the diagnostic steps to confirm a diagnosis 
of ATTR-CM

Infographic showing AL exclusion and ATTR confirmation steps
Patient with Shortness of Breath and LVH

RECOGNISING PATIENTS IN YOUR CLINIC

Explore profiles of patients you may see in your clinic, and understand the signs that led to a diagnosis of ATTR-CM